Cybernetics is defined as:  the science of communication and control processes within systems. Control is based on communication both within the system and with the external environment and influences the actions of the system to bring it into some desired future state or to maintain homeostasis. Cybernetics includes the concepts of auto-regulation and feedback as well as the transmission and self-correction of information, and can be applied not only to machines like computers but also to living organisms, including humans, and to complex organizations and societies.²

Cybernetics then, is the theory of automatic control systems. The nervous system and brain can be viewed as an automatic communication and control system utilizing electrochemical impulses as signals. BEST is also an electrical control system, external to the body, that interfaces directly with the skin and transcutaneously communicates with the internal peripheral nervous system for the purpose of therapeutic intervention. This is possible because of the development of modern high-speed microprocessors, which are able to establish a “cybernetic loop” between electronic instrument and living body. The body’s response can be measured with respect to a signal sent out from the instrument to initiate the loop. When a signal is emitted and penetrates deep into the tissue, the impedance of the tissue (analogous to resistance in DC circuits but dynamic in nature) modulates the waveform of the return signal as it transverses back to the instrument.³ The software inside the instrument may be used to discern and evaluate the signal and modulate the next emitted signal. The degree of modulation is based upon the impedance of the return signal. This sets up a constantly changing interactive bio-loop possessing nonrepeating multiple signals. Eventually the change in impedance signal diminishes in significance until a plateau occurs.

Redox potential is an exceptionally valuable tool for energetic evaluation of cellular metabolism.⁴ It is a representation of overall electron activity within cells and tissues. Oxidation is the loss of electrons and/or hydrogen atoms and/or the gain of oxygen by molecules. Reduction is the gain of electrons and/or hydrogen atoms and/or the loss of oxygen. ^{5 6} It must be clarified that in nature, free electrons do not actually exist in aqueous solutions. They exist in a homogeneous blend and are oftentimes being transferred from one atom or ion to another. Therefore, in living systems it is negative and positive electrical charges that are actually transferred.⁷

The energy is ultimately stored in phosporalated nucleotide bonds like ATP⁸ and ethylene bonds of isoprenoids (vitamins A, D, E, and K), cytochrome, flavinoid, and porphyrin pigments and unsaturated lipids comprising cell membranes.⁹ When tissue becomes saturated by electrical micro-currents, cellular redox potential (charge) is maximized and effective cellular-signaling stimuli are achieved. Impendence increases due to electron saturation. Further signaling past this point is not effective, and the unit automatically signals to cease activity.