A BEST™ device communicates with the neuro-endocrine system through direct touch of the skin, sending a signal through the epidermis and dermis into underlying fascial planes and is transmitted through connective tissue to the C and A nerve fibers.

Connective tissues are comprised of mostly collagen with some elastin. Because of its unique triple helix structure and macro-porous nature, water binds to collagen fibers.¹⁸ The bound layer of water is structured by hydrogen bonding and electrostatic properties of the triple helix and forms a continuum throughout the entire body--a collagen liquid crystal continuum (CLCC). Layers of structured water bound onto collagen fibers provide proton conduction pathways for rapid intercommunication throughout the body. Electro-magnetic energy flows and flux in connective tissues along lines of collagen and flowing along molecules of structured water. The entire fibro-collagen matrix contained in somatic and visceral tissues function as a coherent whole: that is, a continuum.¹⁹ Fibrous collagenous tissue therefore displays the greatest conductivity and least impedance (resistance) to current of all the tissues in the body.²⁰

Ligaments, tendons, and outer capsules of organs and muscles (aponeurosis) are easily apparent. The sheath of areolar tissue invests the entire muscle termed the epimysium.²¹ Muscles encapsulated by epimysium are anatomically grouped based on function, with each muscle forming separate functions of extension or flexion, yet forming spaces or fascial tissue planes between muscle layers. Fascial planes can be viewed as a continuum of interstitial space between muscles, bounded and defined by the epimysiun of muscles. If one studies acupuncture points and meridians, one will observe a correspondence to the fascial muscle planes.²² Points on the skin are very closely aligned with superficial and corresponding subdermal (deep) fascia, especially where multiple fascial planes intersect within the body.

Acupuncture points on the skin are the interface for the CLCC. It has been shown that acupuncture points have much lower electrical impedance (lower resistance and higher conductivity to the flow of electrons) than surrounding skin and are in effect, sumps that will draw electrons (and interestingly enough also photons²³). Electrons flow along fascial planes comprising of CCLC, which define acupuncture meridians.^{21 24} Fibrous capsules and sheaths of nerves, ligaments, tendon, bone (periostium), even fibro-elastic tissue embedded in blood vessels all network in an integrated reticulum to carry electrons throughout the body. Internal organs are encapsulated in the thorax and abdomen with pleural and peritoneal layers, as well as possessing a stromal skeleton, and these also facilitate electron flow. Robert O. Becker defined a perinueral system consisting of epi/peri-neurium and Schwann cells of the peripheral nervous system, and glial, ependymal cells of the central nervous system. Activity is independent of neuronal tracts and propagates a unique electrical current. The perineural system functions as both a support/protective structure and a separate signaling and electron-carrying conduit.^{25 26}

BEST devices actually seek decreased impedance on skin by sticking (dramatic increase in friction) to acupuncture or electron deficient sump points when gliding the instrument over the skin. The area may comprise injured or diseased tissue or may be associated with an organ or corresponding structure with that anatomical segment. Electrons supplied by a BEST unit placed at the correct location on the skin are channeled by the integrated system of connective tissue within the body to the lowest electron deficiency. The normal energetic equilibrium between various tissues and organs is restored, and the redox potential of the body is recharged.